Yes, if the U.S. position involves economic analysis and the applicant holds a baccalaureate or higher degree in the field. The test is the work offered and the degree held, not the applicant's current public-service classification.
The offered work and the degree, in that order
Hypothetical example: the New Maryland applicant's provincial job title is "policy advisor", and the U.S. firm's first draft says "senior analyst". Neither title matters.
What matters is that the U.S. duties are those of an economist, such as building cost-of-service models, forecasting demand and preparing expert testimony on rate design, and that the applicant holds at least a baccalaureate degree in economics. Officers have questioned economist requests where the work was really financial analysis or market research, so the letter should describe the economic content plainly.
Canadian citizenship is required, the position must be prearranged and temporary, self-employment is not permitted, and any ownership stake must be disclosed. Once the profession is fixed, the rest of the sequence follows: gather the degree, choose the procedure, obtain the admission, then give notice. A first review should match each daily function against the profession description and identify the record that proves the applicant's qualification: transcript, degree, licence, or credential evaluation.
It should also identify the company with authority over the work and whether any outside activity would look like an independently run enterprise. Hypothetical example: a hydrologist is offered a role that combines watershed modelling with sales commissions. The reviewer separates technical analysis from client acquisition, asks for a revised duty allocation, and checks whether the listed profession and qualification evidence cover the work that will predominate.
That sequence prevents a polished title from hiding the deciding facts.